Three things piss me off:

1. People on mobile phones
2. People on mobile phones
3. People on mobile phones

If I'm cruising on a highway and there's very little traffic, I'll make a call. But when you're on city streets, you're just a hazard. Personally, I'd rather see someone ripping drunk than on their phone; at least the drunk is trying to pay attention...

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I also hate it when people take Phenergan and Ambien and go out for late-night drives!
(Patrick Kennedy is my representative, I've met him on several occasions, even cooked for him once)